������Ƭ

The CVLP is a national study open at the following hospitals:

• Maidstone & Tunbridge Wells NHS trust
• University Hospital Southampton NHS Trust
• Lewisham & Greenwich NHS Trust
• Royal Surrey County Hospital NHS Foundation Trust
• University Hospitals Sussex NHS Foundation Trust
• East Sussex Healthcare NHS Trust
• Cambridge University Hospitals NHS Foundation Trust
• Barking Havering and Redbridge University Hospitals NHS Trust
• East Suffolk and North Essex NHS Foundation Trust
• Mid and South Essex NHS Foundation Trust
• Univeristy Hospitals Dorset NHS Foundation Trust
• Buckinghamshire Healthcare NHS Trust
• The Hillingdon Hospitals NHS Foundation Trust
• Oxford University Hospitals NHS Foundation Trust
• Nottingham University Hospitals NHS Trust
• South Warwickshire NHS Foundation Trust
• The Royal Wolverhampton NHS Trust
• Walsall Healthcare NHS Trust
• University Hospitals of North Midlands NHS Trust
• Leeds Teaching Hospitals NHS Trust
• Northern Care Alliance NHS Foundation Trust
• Sheffield Teaching Hospitals NHS Foundation Trust
• University Hospitals Plymouth NHS Trust
• Somerset NHS Foundation Trust
• Royal Devon University Healthcare NHS Foundation Trust
• University Hospitals Bristol and Weston NHS Foundation Trust
• North Bristol NHS Trust
• Royal United Hospitals Bath NHS Foundation Trust
• Gloucestershire Hospitals NHS Foundation Trust
• University Hospitals Morecambe Bay NHS Foundation Trust
• East Lancashire Hospitals NHS Trust
• North Cumbria Integrated Care NHS Foundation Trust
• South Tyneside and Sunderland NHS Foundation Trust
• South Tees Hospitals NHS Foundation Trust
• Northumbria Healthcare NHS Foundation Trust
• North Tees and Hartlepool NHS Foundation Trust
• Harrogate and District NHS Foundation Trust
• Manchester University NHS Foundation Trust
• London North West University Healthcare NHS Trust
• Surrey and Sussex Healthcare NHS Trust
• Hampshire Hospitals NHS Foundation Trust
• Chelsea and Westminster Hospital NHS Foundation Trust
• University Hospital Coventry and Warwickshire NHS Trust
• The Dudley Group NHS Foundation Trust
• Chesterfield Royal Hospital NHS Foundation Trust
• Rotherham NHS Foundation Trust
• Great Western Hospitals NHS Foundation Trust
• Milton Keynes University Hospital NHS Foundation Trust
• Bedfordshire Hospitals NHS Foundation Trust
• Hull University Teaching Hospitals NHS Foundation Trust

Please note that not all hospitals will be involved in all of the trials supported by CVLP. You can find a list of the hospitals screening for each of the supported trials on the��Supported Vaccine Trials page.

��

Information for research teams

If you are a researcher or part of a research team at a site already taking part in the CVLP study, more information can be found on the��CVLP Site Resources page. Or contact us through cvlp@soton.ac.uk.

If you are a researcher or part of a research team at a site not already involved in the CVLP and would like more information on joining, please contact us through cvlp@soton.ac.uk.

��

The CVLP is currently supporting the following research trials of cancer vaccines

Advanced melanoma

The SCOPE trial

������Ƭ out more about this trial on the and the .

������Ƭ out more about the CVLP in our Frequently Asked Questions.

This study is accessible through the following CVLP sites:

• North Bristol NHS Trust
• Royal United Hospitals Bath NHS Foundation Trust
• University Hospitals Dorset NHS Foundation Trust
• Gloucestershire Hospitals NHS Foundation Trust
• East Suffolk and North Essex NHS Foundation Trust
• Hull University Teaching Hospitals NHS Trust

��

Head and Neck

BNT113-01 trial

������Ƭ out more about this vaccine trial on the webpage.

������Ƭ out more about the CVLP in our Frequently Asked Questions.

This study is accessible through the following CVLP sites:

• Mid & South Essex NHS Foundation Trust
• Gloucestershire Hospitals NHS Foundation Trust
• University Hospitals Coventry & Warwickshire NHS Trust
• University Hospitals Dorset NHS Foundation Trust
• Royal United Hospitals Bath NHS Foundation Trust
• Hull University Teaching Hospitals NHS Trust
• Bedfordshire Hospitals NHS Foundation Trust
• Royal Surrey NHS Foundation Trust
• Royal Berkshire NHS Foundation Trust
• United Lincolnshire Teaching Hospials NHS Trust
• York and Scarborough Teaching Hospitals NHS Foundation Trust
• Royal Free London NHS Foundation Trust (North Middlesex)

��

Cancer vaccine trials previously supported by the CVLP

Colorectal

BNT122-01 - this trial has now closed to patient recruitment.

������Ƭ out more about this vaccine trial on the .

This study is accessible through the following CVLP sites:

• Maidstone & Tunbridge Wells NHS trust
• University Hospital Southampton NHS Trust
• Lewisham & Greenwich NHS Trust
• Royal Surrey County Hospital NHS Foundation Trust
• University Hospitals Sussex NHS Foundation Trust
• East Sussex Healthcare NHS Trust
• Cambridge University Hospitals NHS Foundation Trust
• Barking Havering and Redbridge University Hospitals NHS Trust
• East Suffolk and North Essex NHS Foundation Trust
• Mid and South Essex NHS Foundation Trust
• Univeristy Hospitals Dorset NHS Foundation Trust
• Buckinghamshire Healthcare NHS Trust
• The Hillingdon Hospitals NHS Foundation Trust
• Oxford University Hospitals NHS Foundation Trust
• Nottingham University Hospitals NHS Trust
• South Warwickshire NHS Foundation Trust
• The Royal Wolverhampton NHS Trust
• Walsall Healthcare NHS Trust
• University Hospitals of North Midlands NHS Trust
• Leeds Teaching Hospitals NHS Trust
• Northern Care Alliance NHS Foundation Trust
• Sheffield Teaching Hospitals NHS Foundation Trust
• University Hospitals Plymouth NHS Trust
• Somerset NHS Foundation Trust
• Royal Devon University Healthcare NHS Foundation Trust
• University Hospitals Bristol and Weston NHS Foundation Trust
• North Bristol NHS Trust
• Royal United Hospitals Bath NHS Foundation Trust
• Gloucestershire Hospitals NHS Foundation Trust
• University Hospitals Morecambe Bay NHS Foundation Trust
• East Lancashire Hospitals NHS Trust
• North Cumbria Integrated Care NHS Foundation Trust
• South Tyneside and Sunderland NHS Foundation Trust
• South Tees Hospitals NHS Foundation Trust
• Northumbria Healthcare NHS Foundation Trust
• North Tees and Hartlepool NHS Foundation Trust
• Harrogate and District NHS Foundation Trust
• Manchester University NHS Foundation Trust
• London North West University Healthcare NHS Trust
• Surrey and Sussex Healthcare NHS Trust
• Hampshire Hospitals NHS Foundation Trust
• Chelsea and Westminster Hospital NHS Foundation Trust
• University Hospital Coventry and Warwickshire NHS Trust
• The Dudley Group NHS Foundation Trust
• Chesterfield Royal Hospital NHS Foundation Trust
• Rotherham NHS Foundation Trust
• Great Western Hospitals NHS Foundation Trust
• Milton Keynes University Hospital NHS Foundation Trust

Patients and potential study participants

This page provides information for study participants and patients interested in finding out more information on joining the CVLP.

Read the Participant Information Sheet

Frequently Asked Questions

How do cancer vaccine trials work?

Cancer vaccine clinical trials are being carried out to find out whether cancer vaccines are safe and effective at helping the immune system to better recognise and attack cancer cells to either slow the growth of the cancer or stop the cancer from coming back. This will be in the form of randomised controlled trials. This means that some patients will receive their usual cancer care in the NHS, or in addition, the cancer vaccine.��

Do cancer vaccines prevent people from getting cancer?

Cancer vaccines are for people who have had a cancer diagnosed and are going through treatment. Cancer vaccines are aimed at helping the immune system to fight against the cancer, but they do not prevent people from getting cancer in the first place.

Why are cancer vaccines not available to everyone who has cancer?

Cancer is different for every person, so there can’t be one cancer vaccine that works for everyone. Different cancers will need to be treated differently, which is why cancer vaccines can either be tailored to each person or to the type of cancer that they have.

What should I do if I’d like to be considered for a cancer vaccine trial?

Your local doctor will be able to let you know if there are any cancer vaccine clinical trials that you might be eligible for and will talk to you about taking part.

Can I receive other treatments at the same time as the vaccination?

Whether you will be able to receive other treatments at the same time is dependent on the clinical trial. Sometimes cancer vaccines are given on their own after you have finished your normal cancer treatment, or they may be given at the same time as your normal cancer treatment. You will be able to receive treatment for any side effects or other conditions you have while receiving treatment with a cancer vaccine.

How long will the clinical trials last?

This will be dependent on the cancer vaccine clinical trial that you are taking part in.

What is the age eligibility?

The eligibility will be dependent on each cancer vaccine clinical trial. Please talk to your local hospital team to see if you are eligible for any cancer vaccine trials.

Are there criteria for taking part in the NHS Cancer Vaccine Launch Pad?

Yes, not everyone will be able to take part in the NHS Cancer Vaccine Launch Pad. Your doctor will be able to let you know if there are cancer vaccine clinical trials that you might be eligible for and will ask you if you would like to take part.

Will I be told which hospital is running the cancer vaccine clinical trial?

Before you consent to the cancer vaccine trial, you will be advised of the closest trial hospital to you. You would need to travel to this hospital to take part in the cancer vaccine clinical trial.

Does my cancer treatment transfer to the cancer vaccine trial hospital?

If you choose to take part in the trial and are eligible, you may receive the vaccine treatment at the hospital running the clinical trial and any standard treatment that needs to be delivered at the same time. If you choose not to take part or are ineligible, you will continue to have your normal cancer treatment at your local hospital.

Where will my normal cancer treatment take place?

Your normal cancer treatment may take place at your local hospital or at the hospital running the clinical trial, depending on whether the vaccine needs to be given at the same time as your normal cancer treatment. Checks to see whether you are eligible for the cancer vaccine trial will take place at the hospital running the clinical trial, as well as the vaccinations if you are confirmed as eligible for the trial.

Will I need to provide a sample of my cancer?

As part of your normal care, you may be having or have already had some or all of your cancer removed. If this has already happened, samples from your previous surgery or biopsy will be used. You will not need to undergo an extra procedure to get a tissue sample for the Cancer Vaccine Launch Pad or cancer vaccine trial.

Will I need to provide any other samples to take part in the NHS Cancer Vaccine Launch Pad?

This is dependent on the cancer vaccine clinical trial that you are being considered for. Some cancer vaccine clinical trials may require a sample of your blood to see if you are suitable to take part.

Will I be reimbursed for my travel to the trial site?

There will be reimbursement available to cover transportation, meals and parking fees for yourself and carer when you have to travel to the hospital running the cancer vaccine clinical trial. This is likely to be arranged by the hospital running the cancer vaccine clinical trial but may be arranged through your local hospital depending on the arrangements of the cancer vaccine trial.

Can I take part in other clinical trials other than for cancer vaccines?

Yes, you can take part in other clinical trials if you are eligible. You can ask your local doctor, nurse or healthcare professional if they know or any clinical trials that you may be eligible to join.

��

The website, which can also be accessed on the NHS App, has information about clinical trials, what taking part might involve and any trials that may be relevant to you. Once you’ve found a study, you can see all the details including who to contact so you can ask to take part. You can also download, save or print the full study details so you can talk to your doctor, nurse or healthcare professional about it.

For some health conditions, you can also find out about clinical trials from the websites of charities.

��

This page provides information for researchers and research teams at sites taking part in the CVLP

Press releases, video clips and other external websites

(University of Southampton cannot accept responsibility for external websites)

��

CVLP explainer video

��

��

CVLP patient story - Aug 2024

BBC Inside Health presenter James Gallagher meets Steve, one of the first patients to recieve a cancer vaccine through the NHS Cancer Vaccine Launch Pad, and discusses the technology behind personalised cancer vaccines.

CVLP launch, May 2024