CCP4: Advanced integrated approaches to macromolecular structure determination

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Staff

Lead researchers

Professor Ivo Tews

Professor

Research interests

Natural products biosynthesis: a complex cascade of catalytic steps in vitamin B6 biosynthesis is characterised by structures or reaction intermediates in the large PLP syntase complexEdit
Bacterial biofilms: understanding of RedOx regulated phosphodiesterase activity in dispersal of biofilms to address chronic infections
Cancer immunology: together with Cancer Immunology at Southampton we use a structure based apporach in developing novel cancer therapie

Connect with Ivo

Email: Ivo.Tews@soton.ac.uk

Collaborating research institutes, centres and groups

Research outputs

Eugene Krissinel, Andrey A Lebedev, Ville Uski, Charles B Ballard, Ronan M Keegan, Oleg Kovalevskiy, Robert A Nicholls, Navraj S Pannu, Pavol Skubák, John Berrisford, Maria Fando, Bernhard Lohkamp, Marcin Wojdyr, Adam J Simpkin, Jens M H Thomas, Christopher Oliver, Clemens Vonrhein, Grzegorz Chojnowski, Arnaud Basle, Andrew Purkiss, Michail N Isupov, Stuart McNicholas, Edward Lowe, Josep Triviño, Kevin Cowtan, Jon Agirre, Daniel J Rigden, Isabel Uson, Victor Lamzin, Ivo Tews, Gerard Bricogne, Andrew G W Leslie & David G Brown, 2022, Acta Crystallographica Section D: Structural Biology, 78(Pt 9), 1079-1089

DOI:

Type: article

Tadeo Moreno-Chicano, Leiah M. Carey, Danny Axford, John H. Beale, R. Bruce Doak, Helen M.E. Duyvesteyn, Ali Ebrahim, Robert W. Henning, Diana C.F. Monteiro, Dean A. Myles, Shigeki Owada, Darren A. Sherrell, Megan L. Straw, Vukica Šrajjer, Hiroshi Sugimoto, Kensuke Tono, Takehiko Tosha, Ivo Tews, Martin Trebbin, Richard W. Strange, Kelvin L. Weiss, Jonathan A.R. Worrall, Flora Meilleur, Robin L. Owen, Reza A. Ghiladi & Michael A. Hough, 2022, IUCrJ, 9(Part 5), 610-624

DOI:

Type: article

Sam Horrell, Danny Axford, Nicholas E. Devenish, Ali Ebrahim, Michael A. Hough, Darren A. Sherrell, Selina L.S. Storm, Ivo Tews, Jonathan A.R. Worrall & Robin L. Owen, 2021, JoVE Journal, 2021(168), 1

DOI:

Type: article

Marina Lučić, Dimitri A. Svistunenko , Michael T. Wilson, Amanda K. Chaplin, Bradley Davy, Ali Ebrahim, Danny Axford, Takehiko Tosha, Hiroshi Sugimoto, Shigeki Owada, Florian S. N Dworkowski, Ivo Tews, Robin L. Owen, Michael A. Hough & Jonathan A. R. Worrall, 2020, Angewandte Chemie International Edition, 59(48), 21656–21662

DOI:

Type: article

Selina L S Storm, Adam D Crawshaw, Nicholas E Devenish, Rachel Bolton, David R Hall, Ivo Tews & Gwyndaf Evans, 2020, IUCrJ, 7(Part 1), 129-135

DOI:

Type: article

John H. Beale, Rachel Bolton, Stephen A. Marshall, Emma V. Beale, Stephen B. Carr, Ali Ebrahim, Tadeo Moreno-Chicano, Michael A. Hough, Jonathan A.R. Worrall, Ivo Tews & Robin L. Owen, 2019, Journal of Applied Crystallography, 52(Pt 6), 1385-1396

DOI:

Type: article

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