View all research projects
Research project

Imaging TB in microspheres

Project overview

We are using multiple imaging approaches to investigate the host-pathogen interaction.

Staff

Lead researchers

Professor Paul Elkington

Director of Inst. for Medical Innovation
Research interests
  • tuberculosis
  • immunopathology
  • diagnosis
Connect with Paul

Email: P.Elkington@soton.ac.uk

Dr Liku Tezera BM, MSc , PhD, FHEA

Senior Research Fellow
Research interests
  • Physiologically relevant in vitro models for chronic bacterial infections that capture host mechanics and microenvironments.TB granuloma mechanobiology.Mechanotransduction pathways, including YAP/TAZ, SRF/MRTF, integrins and TRP channels.Host-directed therapy screening across defined stiffness states.Validating 3D models against patient samples to reduce animal use
Connect with Liku

Email: L.Tezera@soton.ac.uk

Research outputs