Research
Research groups
Research interests
- Eukaryotic Glycobiology
- Carbohydrate-active Enzymes
- Post-translational Modifications
Current research
For an up-to-date list of publications please use the Google Scholar link below:
Our group uses both chemical glycobiology and structural enzymology to understand carbohydrate processing enzymes and the roles they play in living organisms.
Glycosylation and Neurological Disorders
Irregular glycosylation patterns in humans, often caused by defective or absent carbohydrate-active enzymes, underpin a wide range of neurological disorders. Our research focuses on understanding the mechanisms by which these enzymes function, as to provide fundamental insights into disease biology and progression. We apply this knowledge to design chemical tools for research and therapeutic applications.
Fundamental Glycobiology of Eukaryotic Systems
We are also exploring how glycobiology interfaces with regulatory machinery in eukaroytic systems to modulate development, interactions, and stress responses.