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Research project

Dr H M Haitchi ADAM33 gene and environmental interactions in developing lungs and their involvement in the early life origin of asthma

Staff

Lead researchers

Professor Hans Michael Haitchi MD, MMed(INT), PhD, PD, MRCP(London), FHEA, PGcert

Professor
Research interests
  • Study of the asthma susceptibility gene A Disintegrin and Metalloprotease 33 (ADAM33) in early life and adult asthma and other chronic lung diseases.
  • Development of novel Anti-ADAM33 agents as potential disease modifying asthma therapy.
  • Multiomic study of the influence of the maternal environment (e.g. allergic asthma, obesity) during pregnancy on ADAM33 and other mediators and the early origin of lung disease in the Maternal Environment in Pregnancy (MEP) cohort.
Connect with Hans Michael

Email: H.M.Haitchi@soton.ac.uk

Research outputs

Julie A. Cakebread, Hans Michael Haitchi, Yunhe Xu, Stephen T Holgate, Graham Roberts & Donna E Davies, 2014, PLoS ONE, 9(4), e94010-[7pp]
DOI:
Type: article
Alexander W. Lange, Hans Michael Haitchi, Timothy D. LeCras, Anusha Sridharan, Yan Xu, Susan E. Wert, Jeanne James, Nicholas Udell, Philipp J. Thurner & Jeffrey A. Whitsett, 2014, Developmental Biology, 387(1), 109-120
DOI:
Type: article
Gang Chen, Thomas R. Korfhagen, Christopher L. Karp, Soren Impey, Yan Xu, Scott H. Randell, Joseph Kitzmiller, Yutaka Maeda, Hans Michael Haitchi, Anusha Sridharan, Albert P. Senft & Jeffrey A. Whitsett, 2014, American Journal of Respiratory and Critical Care Medicine, 189(3), 301-313
DOI:
Type: article
Philip N. Sanders, Olha M. Koval, Omar A. Jaffer, Anand M. Prasad, Thomas R. Businga, Jason A. Scott, Patrick J. Hayden, Elizabeth D. Luczak, David D. Dickey, Chantal Allamargot, Alicia K. Olivier, David K. Meyerholz, Alfred J. Robison, Danny G. Winder, Timothy S. Blackwell, Ryszard Dworski, David Sammut, Brett A. Wagner, Garry R. Buettner, Robert M. Pope, Francis J. Miller, Megan E. Dibbern, Hans Michael Haitchi, Peter J. Mohler, Peter H. Howarth, Joseph Zabner, Joel N. Kline, Isabella M. Grumbach & Mark E. Anderson, 2013, Science Translational Medicine, 5(195), 195ra97
DOI:
Type: article
Hans Michael Haitchi & Donna E. Davies, 2012
DOI:
Type: bookChapter
Christopher L. Grainge, Valdeep Dulay, Jonathan Ward, David Sammut, Elizabeth Davies, Benjamin Green, Laurie C.K. Lau, Laura Cottey, Hans-Michael Haitchi, Donna E. Davies & Peter H. Howarth, 2012, Respirology, 17(7), 1094-1100
DOI:
Type: article
T.R. Korfhagen, J. Kitzmiller, G. Chen, A. Sridharan, H.M. Haitchi, R.S. Hegde, S. Divanovic, C.L. Karp & J.A. Whitsett, 2012, Proceedings of the National Academy of Sciences, 109(41), 16630-16635
DOI:
Type: article